Resistin and visfatin: are they valuable enough to be the differential diagnosis in familial
Mediterranean fever with acute appendicitis?
Familial
Mediterranean fever is the result of mutations in the MEFV gene encoding pyrin that is a regulatory component of the intracellular inflammasome complex required for the conversion of pro-interleukin (IL)-1[beta] into active IL-1[beta].
Familial
Mediterranean fever is an autosomal recessive disease characterized by recurrent episodes of fever, peritonitis, pleuritis, and arthritis.[2] Previous studies have reported that 90% of patients have abdominal, 75% have articular, and 45% have pleural episodes.
Familial
Mediterranean fever: prevalence, penetrance and genetic drift.
Nailfold capillary abnormalities in patients with familial
Mediterranean fever. Clin Exp Rheumatol 2001; 19: 42-4.
Distribution of the maternal origins of patients with familial
Mediterranean fever and juvenile idiopathic arthritis by geographic regions Note: Table made from Bar-graph Distribution of the paternal origins as percentiles by geographical regions FMF JIA Black Sea 47,3 40,7 Central Anatolia 21,7 11,3 Eastern Anatolia 21,1 21,1 Marmara 3,9 12,8 Southeast 3,6 11,8 Mediterranean 1,7 0,5 Aegeon 0,7 1,6 Figure 2.
Although very atypical in presentation, the diagnosis of familial
Mediterranean fever was considered given the robust response to steroids and his Armenian descent.
Giovinale et al., "Familial
Mediterranean fever: a review for clinical management," Joint Bone Spine, vol.
Clinical disease among patients heterozygous for familial
Mediterranean fever. Arthritis Rheum 2009;60(6):1862-6.
The onset age of disease, disease duration, clinical findings (fever, abdominal pain, chest pain, joint pain, and rash), dose and duration of medication, and
Mediterranean fever mutation were recorded for each patient.
Familial
Mediterranean fever (FMF) is a hereditary autoinflammatory disease characterized by repeated attacks of fever abdominal pain, pleuritic chest pain, and arthritis.
Alghamdi, "Familial
Mediterranean fever, review of the literature," Clinical Rheumatology, vol.