Closure of the defect areas were seen acceleration of the stem cell formation could be seen by increasing of the myeloid tissue and reticular fiber activity and also increased new lamellar bone formation was observed according to maturation of the bone matrix by osteoblasts.
Total amounts of Osteoblastic Activity, Matrix Formation, Trabecular Bone Formation and Myeloid Tissue in Group 2 (p = 0.002), Group 3 (p = 0.002), and Group 4 (p = 0.001) were significantly higher than in Group 1 (Control Group).
No statistical differences were observed in total amounts of Osteoblastic Activity, Matrix Formation, Trabecular Bone Formation and Myeloid Tissue between Group 3 and Group 4.