necrobiosis

[¦ne·krō‚bī′ō·səs]

(medicine)

Death of a cell or group of cells under either normal or pathologic conditions.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Necrobiosis

the change that occurs in a cell prior to cell death. Necrobiosis is linked with metabolic disturbances that may lead to fatty degeneration or to other types of degeneration in the cell. These degenerative changes can be reversible. The most typical symptoms of necrobiosis are changes in the cell nucleus, such as karyopyknosis, karyorrhexis, and karyolysis; disturbances in the viscosity of the cytoplasm; an abnormal staining reaction; and disorganization of the enzyme systems of the cell, which leads to cellular autolysis.

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References in periodicals archive

Barnes, "Necrobiosis lipoidica: Only a minority of patients have diabetes mellitus," British Journal of Dermatology, vol.

Scleredema Diabeticorum with Superimposed Cellulitis and Abscess Formation

Some of the cutaneous markers of diabetes mellitus like necrobiosis lipoidica diabeticorum, diabetic bullae, acquired perforating dermatosis and stiff skin syndrome is not seen in our study.

A descriptive study-cutaneous manifestations of diabetes

Variable histologic findings in postherpetic eruptions include presence of eosinophils or plasma cells within the infiltrate, palisading, necrobiosis, elastosis, elastophagocytosis, interstitial mucin, and lymphocytic cuffing" of histiocyte aggregates in a tuberculoid fashion.

Wolf isotopic response manifesting as postherpetic granuloma annulare: a case series

Does pancreas transplant in diabetic patients affect the evolution of necrobiosis lipoidica?

Unsightly rash on shin: what started as a few small red spots was now an 8 x 6 cm well-demarcated red-brown plaque on the patient's shin. Was it linked to her diabetes?

necrobiosis lipoidica, a progressive condition normally associated with diabetics, five years ago.

I'm confident; Beauty

Necrobiosis appears as one or more shiny, atrophic plaques with visible underlying blood vessels.

Skin signs of internal disease

The differential diagnosis also needs to exclude rheumatoid nodules, necrobiosis lipoidica diabeticorum, and lichen planus.

Ten derm diagnoses pediatricians should make

A differential diagnosis for infections should include necrobiosis lipoidica, noted Dr.

Derm Dx

"I suffer from a condition called necrobiosis, caused by changes in cells of the skin, and it is normally associated with people who have diabetes - which I don't have.

They do a grand job, says Lorna

QI AM a diabetic on insulin, of which I take 76 units a day, and I have a skin disease called Necrobiosis Lipoidica Diabeticorum.

holistic clinic