in the most limited sense, the combining of any substance with oxygen. Generally speaking, “oxidation” describes any chemical reaction that basically involves the removal of electrons from atoms or ions. The most important common oxidizing agents are oxygen (O2), ozone (O3), hydrogen peroxide (H2O2), chlorine (Cl2), fluorine (F2), potassium permanganate (KMnO4), perchloric acid (HClO4), and nitric acid (HNO3).