piperazine

[pī′par·ə‚zēn]

(organic chemistry)

C₄H₁₀N₂ A cyclic compound; colorless, deliquescent crystals, melting at 104-107°C; soluble in water, alcohol, glycerol, and glycols; absorbs carbon dioxide from air; used in medicine.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Piperazine

(or diethylenediimine), a heterocyclic compound; colorless crystals. Melting point, 104°C; boiling point, 145°-146°C. Poorly soluble in water and ether; readily soluble in alcohol.

Piperazine is a strong base. It is obtained by hydrogenation of pyrazine or 2,5-piperazinedione or condensation of dibromo-ethane with ammonia. Piperazine and its derivatives are used in analytical chemistry for microcrystalloscopic identification of Mo, V, and W and in medicine (in the form of salts of adipinic, citric, phosphoric, or sulfuric acid) as an anthelmintic in cases of ascariasis and enterobiasis.

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References in periodicals archive

Synthesis of Poly(phosphoric-boric acid) Piperazine

Synthesis of the Poly(phosphoric-boric acid) Piperazine and Its Application as an Effective Flame Retardant for Epoxy Resins

Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis.

An approach to the new psychoactive drugs phenomenon

Therapeutic trials were conducted to evaluate the clinical efficacy of Piperazine @ 200 mg/kg b.

Comparative Efficacy of Piperazine, Ivermectin and Levamisole in Spontaneous Toxocariasis in Canines based on Faecal Egg Count and Haemato-biochemical changes

Abbreviations EDA: Ethylenediamine PZ: Piperazine MEA: Monoethanol PP: Polypropylene.

Optimization of C[O.sub.2] Absorption Characteristic under the Influence of S[O.sub.2] in Flue Gas by Hollow Fiber Membrane Contactor

Piperazine, which includes benzylpiperazine, a central nervous system stimulant, has been added as a Schedule V drug, with seven of its varieties.

New substances added to prohibited drug list

The piperazine derivatives, a class of amphetamine-like compounds that includes BZP (benzylpiperazine) and TFMPP (trifluoromethylphenylpiperazine) are making a comeback as "legal ecstasy." Often perceived as safe by the public, adverse effects may range from minimal to life-threatening.

Legal highs--not so new and still growing in popularity

Piperazine designer drugs--"party pills"--are synthetic chemical compounds.

Drugs of abuse: a challenging landscape for laboratories

Now you might reasonably expect that this would successfully worm cats but a quick read of the label proved it only contains piperazine.

Vet's always best for pets

To this piperazine (0.001 M) and (0.015 M) formaldehyde were added.

Design, synthesis, characterization, and computational studies on benzamide substituted Mannich bases as novel, potential antibacterial agents

Parsons, "Structures of piperazine, piperidine and morpholine," Acta Crystallographica B, vol.

Investigation on growth, structural, spectral, optical, and mechanical properties of an organic nonlinear optical material: morpholinium hydrogen tartrate

Halazy, "3,6-Dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome C release via bax channel modulation," Journal of Medicinal Chemistry, vol.

Antibacterial activity of murrayaquinone a and 6-methoxy-3,7-dimethyl-2,3-dihydro-1H-carbazole-1,4(9H)-dione

(iii) another peak at [delta] 2.4 (shift from 2.6 to 2.4) in Cipro@C-dots indicates formation of bonds between piperazine moiety of ciprofloxacin and C-dots;

Antibiotic conjugated fluorescent carbon dots as a Theranostic agent for controlled drug release, bioimaging, and enhanced antimicrobial activity