plasmalogen

[plaz′mal·ə·jən]

(biochemistry)

Any of a group of glycerol-based phospholipids in which a fatty acid group is replaced by a fatty aldehyde.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Plasmalogen

any of a group of naturally occurring lipids belonging to phosphoglycerides, or phosphatides. Plasmalogens were first discovered in 1924 in blood plasma. They are widely distributed in animal tissues, for example, the brain, heart, and skeletal muscles, as well as in plant tissues, for example, algae and the fruits of leguminous plants.

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References in periodicals archive

Biochemical investigations like RBC plasmalogen levels and phytanic acid levels could not be done because of financial constraints.

Rhizomelic Chondrodysplasia punctata: a rare case report

Further biochemical studies showed high phytanic acid (9.2; n < 5.28 [micro]mol/L) and low plasmalogen (3.2; n > 6.6) levels.

A case of rhizomelic chondrodysplasia punctata in newborn

Engelmann, "Delayed oxidative degradation of polyunsaturated diacyl phospholipids in the presence of plasmalogen phospholipids in vitro," Biochemical Journal, vol.

Metabolomic Signature of Coronary Artery Disease in Type 2 Diabetes Mellitus

Ether glycerolipid (plasmalogen) biosynthesis: DHAP-ATPase, alkyl-DHAP synthase 4.

Peroxisome biogenesis and human peroxisome-deficiency disorders

Relative high percentages of the plasmalogen derivatives 16:0DMA and 18:0DMA were also detected.

Fatty acid composition and utilization in developing eggs of some marine nudibranchs (mollusca: gastropoda: opistobranchia) from southwest Spain

Analyses of the fatty acid pattern of membrane phospholipids and plasmalogen of human spermatozoa have demonstrated significant levels of polyunsaturated acids.

Effects of dietary fish oil on semen quality of goats

Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination.

Sugarcane Biopolymer as a Guide Tube in the Regeneration of Peripheral Nerves in Rats/ Biopolimero de Cana de Azucar como Tubo Guia en la Regeneracion de Nervios Perifericos en Ratones

Overall, cells treated with 10 [micro]M MEHP showed significantly higher levels of all glycerolipids (FA, MG, DG), PC, PS, phosphatidylserine plasmalogens (PS-P), and phosphatidic acid plasmalogens (PA-P) than cells treated with 0.1 [micro]M MEHP or controls showed.

The Role of Peroxisome Proliferator-Activated Receptor Gamma (PPAR[gamma]) in Mono(2-ethylhexyl) Phthalate (MEHP)-Mediated Cytotrophoblast Differentiation

These products are highly reactive and will oxidize plasmalogens, which are enriched in lung and surfactant, to form chlorinated lipids (Cl-lipids), 2-chloropalmitaldehyde and 2-chlorostearalddehyde.

Halogen Inhalation-Induced Lung Injury and Acute Respiratory Distress Syndrome

Ishikawa et al., "Myo-inositol treatment increases serum plasmalogens and decreases small dense LDL, particularly in hyperlipidemic subjects with metabolic syndrome," Journal of Nutritional Science and Vitaminology (Tokyo), vol.

Inositols in Insulin Signaling and Glucose Metabolism

Juaneda et al., "Red blood cell plasmalogens and docosahexaenoic acid are independently reduced in primary open-angle glaucoma," Experimental Eye Research, vol.

Effects of Oral Supplementation with Docosahexaenoic Acid (DHA) plus Antioxidants in Pseudoexfoliative Glaucoma: A 6-Month Open-Label Randomized Trial