Stress disrupts the lateral
prefrontal cortex control mechanism, but you may be able train people to seek a different strategy, ' he said.
Emotional disorders have been observed in children suffering from ALL after first remission.4 Neural projections from
prefrontal cortex extend to emotion circuits of the brain.
Post-mortem studies have revealed that the inhibitory neurons (which use GABA) in the hippocampi of these individuals are compromised, possibly making it harder for the
prefrontal cortex to regulate activity in this structure.
[9] Other studies have found progressive loss of brain tissues in schizophrenia and reduction of neuronal density decreased in the
prefrontal cortex, as well as (NAA+NAAG) representative neuronal density and activity gradually decreased with the development of disease.
The medial
prefrontal cortex of the 156 mg/kg Allium sativum group showed hypertrophy and hyperplasia especially in the cortical plate.
In addition, a novel miRNA (miR-101b) was found to be downregulated in depression and could decrease mRNA and protein levels of glutamate transporter SLC1A1 in the
prefrontal cortex [59].
They also had less blood flow to the subgenual
prefrontal cortex.
Fuchikami of the department of psychiatry at Yale University in New Haven, Conn., and his coinvestigators placed microinfusions of ketamine into several different areas of the
prefrontal cortex of rat subjects.
They include the hypothalamus; the striatal region, which includes the putamen and caudate and is in charge of motivation and reward; the limbic region, where emotion and memory reside; and the cortical region, which includes the
prefrontal cortex, insula, and the anterior cingulate cortex and handles the integration and processing of the brain.
These studies reported significant impairments in the
prefrontal cortex of antisocial individuals; specifically, impairments were shown in the right orbitofrontal cortex, right anterior cingulate cortex, and left dorsolateral
prefrontal cortex.
The second brain region, a place a little closer to the eyes called the rostromedial
prefrontal cortex, maybe a more sophisticated matchmaker, focusing on personality instead of physical attractiveness.