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renal threshold

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renal threshold

[′rēn·əl ′thresh‚hōld]
(physiology)
A concentration of a substance within the blood which, when reached, causes the substance to appear in the urine.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive
(13) This results in a lower renal threshold for glucose, so UGE occurs at a lower plasma glucose concentration.
Canagliflozin (Invokana) increases glucose excretion, independent from insulin secretion by blocking the transporter (SGLT2) responsible for 90% of glucose reabsorption in the proximal tubules of the kidneys, and lowers the renal threshold for glucose.
Because glucose in the urine competes for reabsorption of 1,5-AG by the kidneys, blood glucose concentrations that exceed the renal threshold [usually approximately 180 mg/dL (10 mmol/L)] reduce the circulating 1,5-AG.
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