Vassetzky, "Short
retroposons in eukaryotic genomes," International Review of Cytology, vol.
Se identificaron cinco loci que servian como sitios de insercion, ademas del locus [beta]-globina en el cromosoma 11 en 9 de los 13 pacientes y los
retroposones LINE-1, los cuales tambien sirvieron, frecuentemente, como blanco de insercion.
They analysed the genomes of the South American opossum and the Australian tammar wallaby, as well as the DNA of 20 other marsupials for a "jumping gene" called
retroposons.
Because
retroposon families derive from transpositionally-active master genes, they conveniently reflect common ancestry.
Ahituv et al., "A Distal Enhancer and an Ultraconserved Exon Are Derived from a Novel
Retroposon," Nature 441 (2006): 87-90; M.
Artiodactyla
retroposons sequences are in uppercase and italic letters and the 49 bp invertion is underlined.
Spadafora, "Expression of LINE-1
retroposons is essential for murine preimplantation development," Molecular Reproduction and Development, vol.
Affara, "The glycerol kinase gene family: structure of the Xp gene, and related intronless
retroposons," Human Molecular Genetics, vol.
Since Alu's are
retroposons, they are transcribed, but only if they are not repressed by methylation, a process controlled by miRNAs.
The sequences thus generated were assembled and analyzed to obtain contigs and singletons, which were further analyzed for the presence of molecular markers, unigenes, ESTs, transposons and
retroposons. This approach can be used in many downstream sequencing processes such as generating comprehensive genetic maps, analyzing the individual chromosomes for variants and minimizing the problems associated with sequence assembly.
Evolutionary history of B1
retroposons in the genus Mus.