Effects of dietary levels of selenium-enriched yeast and
sodium selenite as selenium sources fed to growing-finishing pigs on performance, tissue selenium, serum glutathione peroxidase activity, carcass characteristics, and loin quality.
It can be argued that the studies show no standardization of the formula to be used (selenomethionine or
sodium selenite), which is a relevant factor because they follow different metabolic pathways.
[45] performed an 8-week feeding trial to investigate effects of feed enrichment with
sodium selenite, selenium nanoparticle (nano-Se), selenium yeast (Se-yeast).
First, different doses of
sodium selenite were not given to rats with sciatic nerve injury.
Cataract induced by administration of a single dose of
sodium selenite to sucking rats.
Effect of high-dose
sodium selenite therapy on polymorphonuclear leukocyte apoptosis in non-Hodgkin's lymphoma patients.
[24] conducted a study that evaluated the effect of supplementing diet with 200 [micro]g
sodium selenite per day during 90 days on the level of TPOAb and TgAb in patients with autoimmune thyroiditis; 71 patients with autoimmune thyroiditis under therapy with levothyroxine and with high levels of TPOAb and/or TgAb were evaluated.
Supplemental Se sources are supplied as an inorganic complex, such as
sodium selenite (Na2SeO3) or as part of organic molecules, such as selenomethionine from selenized yeast.
Liver mor-phology and histochemistry in rats resulting from inges-tion of
sodium selenite and sodium fluoride.
A role for Se in Ebola treatment is also supported by the results of Chinese researchers, who treated patients in an outbreak of viral haemorrhagic fever with oral
sodium selenite, obtaining dramatic reductions in mortality: after 9 days of Se dosage, the death rate fell from 100% (untreated) to 37% (treated) in the very severe cases, and from 22% to zero in the less severe cases (Hou, 1997)