Those on
St John's wort reported 172 adverse effects.
The herb
St John's wort, has two unique components, hypericin and hyperforin, which have an antidepressant action.
The two major constituents of
St John's wort, hypericin and hyperforin, have been shown to possess substantial medicinal activity, while other compounds including the flavonoids rutin, quercetin and kaempferol also appear to have medicinal properties (Klemow 2011).
Co-treatment with
St John's Wort 300 mg three times daily was then added for two additional 28-day menstrual cycles.
The mice were treated with either buspirone (10mg/kg), fluoxetine (10mg/kg), imipramine (20mg/kg), diazepam (5mg/kg), St Johns wort (Hypericum perforatum) (125mg/kg, 250mg/kg, 500mg/kg, 750mg/kg or 1000mg/kg) or various single constituents found in
St John's wort (SJW).
They may cause severe growth retardation leading to changes in the chemical content and thus to alteration of the quality/market value of
St John's wort preparations.
The
St John's Wort had prevented her anticonvulsant medication from working.
St John's Wort, a supplement taken to alleviate mild to moderate depression, is known to counteract the effect of certain drugs, including hormonebased contraceptives.
Q I'M a keen believer in alternative medicine and for several months I've been taking extract of
St John's Wort for mild depression.
Q I'VE had a kidney transplant and have been told not to take
St John's wort for depression.
The Government yesterday issued an urgent health warning over the herbal remedy
St John's Wort amid fears it can stop other drugs from working.