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TATA box

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TATA box

[′tä‚tä ‚bäks or ¦tē¦ā¦tē′ā ‚bäks]
(genetics)
In eukaryotes, a short sequence of base pairs that is rich in adenine (A) and thymidine (T) residues and located about 25-30 nucleotides upstream of the transcriptional initiation site.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive
Dynamics of TBP binding to the TATA box. 2008 Proceedings of SPIE, 6862: 68620E-1-8.
Large T antigen binds preferentially to a site (TAg) located in the viral DNA ori, closest to first TATA box in the NCCR.
Furthermore, we were isolated the [beta]-casein gene containing the mutant TATA box (CATAAAA) by LA-PCR of samples from another individual pig (Figure 2A).
In our model, activation of the construct via promoter sites other than the EREs is avoided by using only a minimal TATA box in the construct, resulting in low background activity.
Hoechst 33342 induces apoptosis and alters TATA box binding protein/DNA complexes in nuclei from BC3H-1 myocytes.
Among 93 patients with the six-pair TATA box, 14, or 15%, experienced severe side effects from irinotecan hydrochloride.
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