Clinical significance of
thrombocytosis before preoperative chemo-radiotherapy in rectal cancer: predicting pathologic tumour response and oncologic outcome.
Impact of preoperative
thrombocytosis on prognosis after surgical treatment in pathological T1 and T2 renal cell carcinoma: results of a multi-institutional comprehensive study.
There is increasing evidencethat abnormal expression of pro-inflammatory cytokines in chronic inflammation may lead to unregulated clonal proliferation.1 Although,
thrombocytosis may occur in Rheumatoid arthritis (RA) as reflection of high inflammatory state, true primary or essential
thrombocytosis (ET) is extremely rare.
Furthermore,
thrombocytosis (330-593 x 109/L) was noted.
Thrombopoietic cytokines in patients with iron deficiency anemia with or without
thrombocytosis. Acta Haematol 2000;103:152-6.
Several papers have shown that
thrombocytosis is a useful prognostic indicator for postoperative outcomes in patients with malignancy.
In most patients with PV, elevated hemoglobin > 18.5 g/dL is associated with
thrombocytosis (platelet count > 450,000/[micro]L in 53%) [6].
Lab results showed microcytic anemia with hemoglobin of 6 g/dL, and
thrombocytosis, with a platelet count of 512,000.
Prognostic factors evaluated were tumor histology, grade, depth of myometrial invasion, maximum tumor diameter, lymphovascular invasion, nodal status, elevated CA-125, and
thrombocytosis. Grade 1 and 2 tumors were classified as low grade; grade 3 tumors were classified as high grade.
Key words: Demographic features, Myeloproliferative disorders,
Thrombocytosis.