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Tropomyosin

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tropomyosin

[‚träp·ə′mī·ə·sən]
(biochemistry)
A muscle protein similar to myosin and implicated as being part of the structure of the Z bands separating sarcomeres from each other.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Tropomyosin

 

a protein constituent of muscle myofibrils. Tropomyosin A, or paramyosin, is insoluble in water, in contrast to water-soluble tropomyosin B. Paramyosin is found in the muscles of mollusks and of some arthropods, where it is believed to occupy the center of thick myosin fibers. Tropomyosin B, actin, and myosin are the principal proteins of skeletal muscles and constitute about 11 percent of myofibril protein. Tropomyosin B is a constituent of the thin fibers of I disks (isotropic disks).

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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The symptoms of systemic anaphylaxis were measured before and after tropomyosin challenge and scored based on a scoring system [48]: 0, no symptoms; 1, scratch and rub nose and head; 2, swelling eyes and mouth, diarrhea, slow or no activity with an increased respiratory rate after prodding; 3, wheezing and cyanosis around the mouth and the tail; 4, no activity; and 5, death.
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Caption: Figure 3: Densitometric profile and SDS-PAGE of a pool of 15 myofibrillar extracts obtained from beef, lamb, and chicken samples extracted with denaturing (a) and nondenaturing (b) solutions (1 = myosin heavy chain; 2 = 180-110 kDa; 3 = [alpha]-actinin; 4 = 95-55 kDa; 5 = desmin; 6 = 51-47 kDa; 7 = actin; 8 = 39 kDa; 9 = troponin T; 10 = tropomyosin; 11 = 33-23 kDa; 12 = myosin light chain 1; 13 = 21-18 kDa; 14 = troponin C; 15 = myosin light chain 2; 16 = 14-10 kDa).
Methods for Extraction of Muscle Proteins from Meat and Fish Using Denaturing and Nondenaturing Solutions
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Soto, "Nuclear tropomyosin and troponin in striated muscle: new roles in a new locale?" Journal of Muscle Research and Cell Motility, vol.
The Cooccurrence of Obesity, Osteoporosis, and Sarcopenia in the Ovariectomized Rat: A Study for Modeling Osteosarcopenic Obesity in Rodents
Assembly of different isoforms of actin and tropomyosin into the skeletal tropomyosin-enriched microfilaments during differentiation of muscle cells in vitro.
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Both of sarcomeric and cytoplasmic actin filaments are usually associated with tropomyosin. Tetrahymena actin, which cannot bind rabbit skeletal tropomyosin, is a rare exception.
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Tropomyosin receptor kinases (TRKA through TRKC) bind the neurotrophin family of ligands, including nerve growth factor, and have been implicated in tumorigenesis.
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The putative heat stable proteins identified were myosin light chain (MLC), actin, tropomyosin (TPM), troponin T (TnT), myoglobin, and creatine kinase.
A PROTEOMIC BASED ASSESSMENT ON CHANGES IN MYOFIBRILLAR PROTEINS OF GOAT LONGISSIMUS MUSCLE AS AFFECTED BY HEAT TREATMENTS
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