Furuichi, "Prevalence of
Werner's syndrome heterozygotes in Japan," Lancet, vol.
DISCUSSION:
Werner's syndrome is a rare autosomal recessive disorder.
Review of two siblings with
Werner's syndrome. Case Report Med 2009: 2009; 1383-12
People with
Werner's syndrome show signs of accelerated aging in their 20s, develop age-related diseases and generally die before age 50.
Werner's syndrome is the second form of Progeria and starts in adolescence or early adult life then follows the same rapid progression as the juvenile form.
Researchers have already gained much insight from the study of
Werner's syndrome, a rare genetic disorder in which the normal aging clock is dramatically and disastrously accelerated.
Recent support for a central role of repair systems in ageing came from isolation of the gene for
Werner's syndrome, a rare condition associated with premature ageing [21].
The impact of certain ancient genes on aging in humans can be seen in inherited aging diseases like
Werner's syndrome. This is a type of disorder called a progeria, in which humans race through an aging-like process at a greatly accelerated pace.
Young people with
Werner's syndrome acquire gray hair and diseases such as osteoporosis, cataracts, and hardening of the arteries.
Keywords: age-related disease, Cockayne's syndrome, Hutchinson-Gilford progeria, premature ageing syndromes, senescence-accelerated mouse,
Werner's syndromeAlthough there are real-life aging disorders, such as Progeria, Agrogeria and
Werner's Syndrome, the ailment Jack suffers in the movie is invented.