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analgesic

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analgesic

1. of or causing analgesia
2. a substance that produces analgesia
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005

analgesic

[‚an·əl′jēz·ik]
(pharmacology)
Any drug, such as salicylates, morphine, or opiates, used primarily for the relief of pain.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Analgesic

 

a medicinal substance that relieves pain. Analgesics are a structurally varied group of medicines. Narcotic analgesics (seeNARCOTIC) are distinguished from nonnarcotic analgesics. The latter group comprises derivatives of salicylic acid, pyrazolone, aniline, and indole; in addition to being analgesics, these derivatives are antipyretics and anti-inflammatories. Amidopyrine, analgin, butadion, phenacetin, acetyl-salicylic acid, and other similar preparations are used for musculoarticulatory pains, neuralgias, headaches, and toothaches, but they are only mildly effective against acute pain caused by traumas or spasms in the smooth musculature.

Analgesics alter the body’s sensitivity to pain by predominantly affecting brain centers and/or the pituitary-adrenal system. Nonnarcotic analgesics, in contrast to narcotic analgesics, anesthetizing remedies, and anesthetics (seeANESTHETIC), do not influence any senses other than touch and do not affect mental functioning or the coughing and respiratory centers. Furthermore, nonnarcotic anesthetics are not somnifacient or addictive. (SeeANTIPYRETICS.)

REFERENCES

Zakusov, V. V. Farmakologiia nervnoi sistemy. Moscow, 1953.
Zakusov, V. V. Farmakologiia. Moscow, 1966.
Mashkovskii, M. D. Lekarstvennye sredstva, part 1. Moscow, 1972.
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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References in periodicals archive
Separate involvement of the spinal noradrenergic and serotonergic systems in morphine analgesia: the differences in mechanical and thermal algesic tests.
Physical self-regulation can eliminate negative oral habits and maintain more relaxed muscles, avoiding the ischemia and accumulation of algesic intramuscular and articular substances.
Algesic effects in both models are said to be due to liberation of mediator substances like sensory neuropeptides and prostaglandins (Henry et al., 1999; Sandor et al., 2007).
Evidence-informed management of chronic low back pain with nonsteroidal anti-inflammatory drugs, muscle relaxants, and simple an algesics. Spine J.
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