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amantadine

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amantadine

[ə′man·tə‚dēn]
(pharmacology)
C10H17N A symmetrical amine used as a viral chemoprophylactic because it selectively inhibits certain myxoviruses; also of value in the treatment of parkinsonism.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
Generic pharmaceutical company Lannett Company Inc (NYSE:LCI) reported on Friday the receipt of approval for its Abbreviated New Drug Application (ANDA) for Amantadine Hydrochloride Capsules USP, 100 mg from the US Food and Drug Administration (FDA).
Lannett wins US FDA approval for Amantadine Hydrochloride Capsules USP, 100 mg
However, slowly administered intravenous physostigmine in 1 and 2 mg doses in an adult2 at 1- to 2-hour intervals and 0.5 mg doses in a child3 at 5- to 10-minute intervals up to a maximum of 2 mg/hour have been reported to be effective in the control of central nervous system toxicity caused by Amantadine hydrochloride. For acute overdosing, general supportive measures should be employed along with immediate gastric lavage or induction of emesis.
Effect of amantadine on serumic levels of creatinine in native poultry
Efficacy and safety of low dosage amantadine hydrochloride as prophylaxis for influenza A.
Adamantane-resistant influenza infection during the 2004-05 season
Experiments on cells taken from fish and other animals are three times as effective as amantadine hydrochloride, the widely available basis of many modern flu remedies.
Can laverbread cure the flu?; Scientists say substance isolated from seaweed is effective at fighting virus
The 4 approved therapeutic medications (amantadine hydrochloride, rimantadine hydrochloride, zanamivir, and oseltamivir) must be started within 30 to 48 hours of initial symptoms for any appreciable benefit to the patient, yet only a small fraction of patients present to their primary care providers within this time frame.
LETTERS to the Editor
Morton Grove, another manufacturer and marketer of a broad line of generic drugs, was granted its first ANDA approval of this year for amantadine hydrochloride syrup USP 50 mg./5 ml.
FDA Approves Array of Generic Medications
Antiviral agents available for the prophylaxis or treatment of influenza type A infection are amantadine hydrochloride and rimantadine hydrochloride.
Update: influenza activity - worldwide, 1996
There is one prescription antiviral medicine, amantadine hydrochloride, that can shorten the course of one serious form of influenza if taken shortly after its onset.
The best medicine for the flu
The United States Food and Drug Administration has received a New Drug Application (NDA) from United States-based Adamas Pharmaceuticals for its ADS-5102 (amantadine hydrochloride) extended-release capsules, the company's lead product candidate, it was reported on Friday.
US FDA receives New Drug Application from Adamas Pharmaceuticals for ADS-5102
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