Aminophylline is a common, cheap medication given to prevent and treat asthma and other lung diseases.
The study subjects were randomized to receive either Drug A (
Aminophylline, n=20) or Drug B (Caffeine, n=20).
The continuation of maintenance oral theophylline appears reasonable, but the use of intravenous
aminophylline has no therapeutic benefit, is associated with increased adverse events, and should be removed from the guideline.
TABLE Theophylline use in asthma Adults Children Acute No added benefit to 24 hours of IV Treatment corticosteroids and
aminophylline improves beta-agonist therapy; symptom scores without increased GI and cardiac reducing LOS or side effects.
Other obesity researchers point to the short-term (24-hour) results from applying
aminophylline, indicating interstitial fluids are temporarily displaced allowing for a "less watery" thigh for a day or two.
Bruce Frome, who is involved in licensing the creams, women have high levels of a fat-conserving enzyme in their thighs and breasts, and
aminophylline blocks this enzyme.
The NMC says that Sanchez "failed to administer 960mg of
aminophylline...
After skin closure
aminophylline 4mg/ kg was given to Group A and an equivalent volume of normal saline to Group P.
Skin Zone contains
aminophylline and alpha-hydroxy acids.
Aminophylline, a prescription asthma drug, is the controversial new ingredient in the much-lauded thigh cream.
The clinical algorithim found on page 210 is not in keeping with recent NIH guidelines, which stress the use of inhaled [beta]-agonists in place of
aminophylline. Quite a few of the diagrams detailing pathophysiologic mechanisms were not useful in the context of the diagnostic and therapeutic information presented.