Fluorescence in situ hybridization detects increased sperm
aneuploidy in men with recurrent pregnancy loss.
Aneuploidy (an abnormal number of chromosomes) is the most frequent genetic disorder observed in live births and miscarriages, with trisomies being the most prevalent, accounting for approximately 53 percent of all chromosome abnormalities.
Rapid diagnosis of
aneuploidy in chromosomes 13, 18, 21, X and Y by quantitative fluorescence-PCR combined with short tandem repeat and fluorescence-labeled homologous gene quantitativePCR using 4-color fluorescently labeled universal primers.
Rapid, high throughput prenatal detection of
aneuploidy using a novel quantitative method (MLPA).
Is it time to sound an alarm about false-positive cell-free DNA testing for fetal
aneuploidy? Am J Obstet Gynecol 2013;209:415-9.
Growth in this segment can be attributed to the increasing maternal age, rising incidence of
aneuploidy disorders, and strategic initiatives by key players to provide technologically advanced PGS products for
aneuploidy screening.
With the recent impetus on first-trimester screening for
aneuploidy and availability of high-resolution transducers, agenesis of DV can be diagnosed in the first trimester.
Of the total number of second-trimester ultrasound scans done (n=66), 14 (21.2%) detected a variety of markers of
aneuploidy. Eight of these patients only had a second-trimester ultrasound scan, and 6 had prior CFTS.
DNA sequencing versus standard prenatal
aneuploidy screening.
[sup][1],[2] Chromosome
aneuploidy and polyploidy consist of more than 96% of chromosomal abnormalities in spontaneous abortion and X, Y, 13, 16, 18, 21, and 22 are frequently involved.
All carcinogens cause
aneuploidy, even though they may not cause genes to mutate.