Anisocytosis and anisokaryosis were moderate; occasional fine pink extravascular material was associated with cell aggregates.
It thus postulated that it is conceivable that the free cholesterol in excess within the primary atherosclerotic lesion may originate from other cellular sources, including RBCs, and that
anisocytosis may directly participate in the pathogenesis of cardiovascular disease (CVD) through a variety of mechanisms.
They thought that inflammation and thromboembolism resulted with
anisocytosis, causing elevation of RDW (5).
At approximately 16 months of age, a complete blood count (CBC) showed a platelet count of 104,000/uL, increased red cell distribution width (RDW, 17.1%),
anisocytosis, and microcytosis.
They suggested a possible mechanism of the adverse effects of chronic inflammation on erythropoiesis and thus
anisocytosis occurrence via direct erythroid precursor's suppression reduces the production of erythropoietin by kidneys, reduces the iron bioavailability, and induces apoptosis and increases the resistance to erythropoietin of the erythroid precursor cell line.
Urch et al., "Clinical and prognostic significance of
anisocytosis measured as a red cell distribution width in patients with colorectal cancer," QJM, vol.
Blood film showed
anisocytosis and small number of pencil cells.
Hypochromic microcytic red cell in proportion to degree of anaemia, with poikilocytosis
anisocytosis, pencil cells, red cell count less than 5 million/mm3 and MCV less than 75fl usually favors iron deficiency.
The most important diagnostic feature of cancer cells are anisonucleosis,
anisocytosis, abnormal nuclear texture and nuclear hyperchromasia and abnormal N/C ratio.
Red cell distribution width (RDW) is a quantitative measurement of difference in the size of circulating erythrocytes, which has a high value if greater heterogeneity in cell dimensions is present (i.e.,
anisocytosis).