Although it was patented back in .1957 as the world's first antifungal, antibiotic nystatin upstaged newer
antifungal agents when used to treat vulvovaginal candidiasis caused by Candida glabrata in sequential, prospective clinical trials.
Luliconazole is one of the most potent and broad-spectrum topical
antifungal agents. TOPICA is developing luliconazole for onychomycosis, which affects approximately 35 million people in the U.S.
Since the cell wall is essential for fungal cell survival and because human cells do not have walls, this structure continues to be considered a principal target for the development of
antifungal agents (2).
Tolnaftate is an over-the-counter
antifungal agent that has been available in the US since 1965.
Micatin, an
antifungal agent for athlete's foot, has been available over the counter since 1983.
It turns out that the
antifungal agent is also an inhibitor of the Hedgehog pathway, and via a different mechanism than that of vismodegib and sonidegib.
As this study was noninterventional, the choice of
antifungal agent prescribed was left to the primary physicians.
Use of Punica granatum as an
antifungal agent against candidosis associated with denture stomatitis.
Many biologists believe the toxicity of silver nanoparticles, the reason for their use as an antibacterial or
antifungal agent, is due to their high surface area that makes them an efficient source of silver ions, he says, but "this creates the idea that there may be some sort of natural cycle returning some of the ions to nanoparticles." It also helps explain the discovery, over the past few years, of silver nanoparticles in locations like old mining regions that are not likely to have been exposed to human-made nanoparticles, but would have significant concentrations of silver ions.
Its use as an
antifungal agent in resilient liners has not been investigated.
species.9 Recently, the Clinical and Laboratory Standards Institute (CLSI) described that the clinical efficacy of each
antifungal agent relates to the MIC as it gives the MIC breakpoint for susceptibility of <2ug/ml for C.
PC945 is the first triazole
antifungal agent to be developed for delivery to the lung via inhalation.