Arachis oil (Acros Organics, Belgium) was employed as vehicle.
DES (5 [micro]g/kg) or vehicle (
arachis oil) were administered by subcutaneous (sc) injection (dosing volumes for rats and mice were 2.5 and 5 mL/kg, respectively) daily for 3 days to two additional groups of animals housed in the same room as the control untreated animals (i.e., in the absence of males).
The 109 eligible patients were randomized in a double-masked fashion, in blocks of 10, to receive either a single 60 000 [micro]g retinol equivalent (200 000 IU) dose of vitamin A (n = 53) or an identical placebo capsule (n = 56) containing 300 retinol equivalents (1000 IU) as retinyl palmitate in
arachis oil (Roche, Basel, Switzerland).
The Working Party has prepared a draft position paper on the use of herbal medicinal products containing
Arachis oil and preparations from Soya bean.
(fine ground) as above but containing either 2%
arachis oil alone (control mice) or 2%
arachis oil and 1% griseofulvin (w/w) obtained from Sigma Ltd.