lb, the characteristic absorption peaks appearing near 1,630, 1,500, and 1,270 [cm.sup.-1] correspond to the N-H characteristic peak of DA, the stretching vibration peak related to C-C of benzene ring, and C-N of
arylamine, respectively [26].
3-Amino-4-hydroxybenzaldehyde (6a) is an intermediate of grixazone synthesis in Streptomyces griseus (a species of soil Actinomycetes), and aryl amine group is acetylated by cytosolic enzymes;
arylamine N-acetyltransferases (NATs).
We read with interest the article by Fayez et al entitled "
Arylamine N-acetyltransferase 2 Polymorphisms and the Risk of Endometriosis" (1) that was recently published in your journal.
Chen, "
Arylamine organic dyes for dyesensitized solar cells," Chemical Society Reviews, vol.
Rodrigues-Lima, "Impairment of the activity of the xenobiotic-metabolizing enzymes
arylamine N-acetyltransferases 1 and 2 (NAT1/NAT2) by peroxynitrite in mouse skeletal muscle cells," FEBS Letters, vol.
Carbon black nanoparticles impair acetylation of aromatic amine carcinogens through inactivation of
arylamine N-acetyltransferase enzymes.
The NAT2 functions to both activate and deactivate
arylamine and hydrazine drugs and carcinogens.
Berberine inhibited
arylamine N-acetyltransferase activity and gene expression and DNA adduct formation in human malignant astrocytoma (G9T/VGH) and brain glioblastoma multiforms (GBM 8401) cells.
Effects of (-)-menthol on
arylamine N-acetyltransferase activity in human liver tumor cells.
Sulfacontaining antibiotics contain a five- or six-member nitrogen-containing ring attached to the N1 nitrogen of the sulfonamide group and an
arylamine group (H N) at the N4 position of the sulfonamide group (Pharmacotherapy 2004;24:856-70).