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auxotrophic mutant

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auxotrophic mutant

[¦ȯk·sə¦trä·fik ′myüt·ənt]
(genetics)
An organism that requires a specific exogenous growth factor, such as an amino acid, for its growth.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
Use of uridine auxotrophy (ura3) for markerless transformation of the mycoinsecticide Beauveria bassiana.
Construction of Isaria fumosorosea Blastospore-Transforming System by Agrobacterium-Mediated Transformation with Benomyl-Resistance Gene
(2011) The genome of thl7 cell-inducing segmented filamentous bacteria reveals extensive auxotrophy and adaptations to the intestinal environment.
Use of gnotobiotic mice to identify and characterize key microbes responsible for the development of the intestinal immune system
Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1trial of CVD 1204 and CVD 1208.
Expression of Shigella flexneri ipaB gene in tobacco
ANEp2 was used to functionally test for complementation of uridine auxotrophy and reporter gene expression in an A.
Development of a pyrG mutant of Aspergillus oryzae strain S1 as a host for the production of heterologous proteins
Furthermore, a purine and pyrimidine metabolism, pathways for canonical amino acids, were identified, rendering auxotrophy an unlikely event (Siegl et al., 2011).
Exploring symbioses by single-cell genomics
coli showed auxotrophy that can be suppressed by a rpoB mutation ([beta]T563P), which also suppresses the auxotrophy of a (p)ppGpp negative strain, called [(p)ppGpp.sup.0] strain (17).
Genetic components of stringent response in Vibrio cholerae
aureus, confirmed by polymerase chain reaction amplification of the nuc and coa genes as well as by determination of the strain's auxotrophy for hemin.
Small colony variants of Staphylococcus aureus and pacemaker-related infection
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