capillary gel electrophoresis

[¦kap·ə·ler·ē ¦jel i‚lek·trō·fə′rē·səs]

(analytical chemistry)

A form of capillary electrophoresis in which a polyacrylamide gel (or other polymeric material) is placed inside the capillary and separation is based on size and charge; often used to separate oligonucleotides and proteins.

References in periodicals archive

Here we report a quantitative PCR method, followed by separation by capillary gel electrophoresis of the fluorescently labeled amplified exons of hot spot regions of the dystrophin gene, which allowed us to detect ~99% patients (affected males and female carriers) with macrodeletions and 89% with macroduplications, and to identify small insertions or deletions in those regions.

Direct detection of exon deletions/duplications in female carriers of and male patients with Duchenne/ Becker muscular dystrophy

High-resolution capillary gel electrophoresis of reducing oligosaccharides labeled with 1-aminopyrene-3,6,8-trisulfonate.

Determination of D-mannose in serum by capillary electrophoresis

This method can easily be implemented into a minimally equipped laboratory, and the detection of the PCR products can be automated by the use of capillary gel electrophoresis. However, a technical failure in the PCR could lead to misclassification of a patient's Apo E genotype.

Rapid identification of Apolipoprotein E genotypes by multiplex amplification refractory mutation system PCR and capillary gel electrophoresis

Prediction of migration behaviour of oligonucleotides in capillary gel electrophoresis. J Chromatogr 1992; 593:297-303.

Chemical mismatch cleavage combined with capillary electrophoresis: detection of mutations in exon 8 of the cystathionine [beta]-synthase gene

Capillary gel electrophoresis (CGE) in molecular pathology and genetics is an ideal instrument for fast, fully automated analysis.

Capillary electrophoresis in the analysis of the deletion/insertion polymorphism of the angiotensin I-converting enzyme gene