For this reason, it is stated that suitable
carrier protein conjugates should be used (9).
LE-localized ABCG1 stimulated cholesterol transfer from the LE to PM, perhaps by direct interaction between LE and PM membranes, and/or in a process, mediated by nonvesicular cytosolic cholesterol
carrier proteins such as OSBP [160].
stewartii uses 3oxohexanoyl acyl
carrier protein and SAdenosylL Methionine (SAM) as substrates to make 3oxohexanoyl homoserine lactone (AHL) autoinducers.
The second step in non-ribosomal peptide biosynthesis is the transfer of the activated aminoacyl moiety from the adenylate to the thiol group of the adjacent
carrier protein domain.
Battesti and Bouveret (6) have shown that during fatty acid starvation (p)ppGpp synthetase activity of SpoT is regulated through an interaction of the TGS domain of the enzyme with the acyl
carrier protein (ACP), a central co-factor in fatty acid biosynthesis.
The nonprofit group, which gets much of its financing from the Bill and Melinda Gates Foundation, will also pay the FDA about $480,000 for its work on the project, which will include improving the conjugation technology that links a piece of the bacterium's surface coating, a polysaccharide made up of long chains of sugars, to a special molecule called a
carrier protein. That process, called conjugation, is needed to increase the strength of the immune response.
259) hypothesized that associations might be modified by a common variant allele of the aminolevulinic acid dehydratase (ALAD) gene, which encodes the primary
carrier protein for lead in blood.
The reference gene are stearoyl
carrier protein desaturase 2 (SAD)", said a Danish Plant Directorate spokesman.
The biosynthesis of omega-3 in deep-sea bacteria takes place not by the desaturation and elongation of saturated fatty acids, but rather by a polyunsaturated fatty acid (PUFA) synthase system which resembles a PKS in that it builds the fatty acid one acyl unit at a time, introducing the double bonds as the chain grows attached to an acyl
carrier protein (35).
Triclosan is known to act on enoyl-acyl
carrier protein reductase, called Fab 1.
Further development was undertaken; the Hib polysaccharide was conjugated to a
carrier protein and this process then gave an effective vaccine that could be administered to the under 2-year age group.