The difference between the thiocolchicoside and
chlorzoxazone group before and after administration of the respective drugs were compared using unpaired t-test.
Interindividual variability of
chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms.
The list of potentially inappropriate drugs included propoxyphene, indomethacin, pentazocine, methocarbamol, carisoprodol, oxybutynin,
chlorzoxazone, metaxalone, cyclobenzaprine, flurazepam, amitriptyline, doxepin, meprobamate, lorazepam, oxazepam, alprazolam, temazepam, zolpidem, triazolam, chlordiazepoxide, diazepam, hydroxyzine, promethazine, all barbiturates (except phenobarbital), and meperidine.
The list of potentially inappropriate drugs included: propoxyphene, indomethacin, pentazocine, methocarbamol, carisoprodol, oxybutynin,
chlorzoxazone, metaxalone, cyclobenzaprine, flurazepam, amitriptyline, doxepin, meprobamate, lorazepam, oxazepam, alprazolam, temazepam, zolpidem, triazolain, chlordiazepoxide, diazepam, hydroxyzine, promethazine, all barbiturates (except phenobarbital), and meperidine.
The list included propoxyphene, indomethacin, pentazocine, methocarbamol, carisoprodol, oxybutynin,
chlorzoxazone, metaxalone, cydobenzaprine, flurazepam, amitriptyline, doxepin, meprobamate, lorazepam, oxazepam, alprazolam, temazepam, zolpidem, triazolam, chlordiazepoxide, diazepam, hydroxyzine, promethazine, all barbiturates (except phenobarbital), and meperidine.
These include tricyclic antidepressants, neuroleptics, beta-blockers and other antiarrhythmics (CYP2D6); paracetamol,
chlorzoxazone and ethanol (CYP2E1) and hydrazines, arylamines, pyrazolones, caffeine and nitrazepam (NAT2) among others.
Four weeks after being discharged, the patient no longer required muscle relaxants (
Chlorzoxazone) and was able to perform most of her activities of daily living without pain.
The muscle relaxant
chlorzoxazone (Algisin, Paraflex, Parafon Forte), the antibiotic rifampin (Rifadin, Rofact), antipsychotics, and some antiparasitic medications may cause spectacular colorations in urinary discharge.