chronic granulomatosis

[′krän·ik ‚gran·yə‚lō·mə′tō·səs]

(medicine)

A disorder of the phagocytes in which they ingest bacteria normally but fail to kill them; disease is usually fatal due to overwhelming bacterial infection.

References in periodicals archive

Tokyo, Japan, Jan 11, 2007 - (JCN) - Bio affiliate ViroMed Co., Ltd., based in Korea, announced the Korea Food & Drug Administration approval of their clinical trial of VM106, gene therapy treatment drug, for chronic granulomatosis.

Takara Bio Obtains Clinical Trial Approval of Gene Therapy Treatment for Chronic Granulomatosis

In addition, a killing test to evaluate macrophage activity was performed, and a diagnosis of chronic granulomatosis disease was excluded.

Mycobacterium lentiflavum infection in immunocompetent patient

* Chronic Granulomatosis Disease (CGI)) which is caused by a defect in the phagocytic cells, affecting 1/200,000.

Raising nurses' awareness of primary deficiency: primary immune deficiency is a term covering a large family of diseases and conditions in which the patient's immune system is compromised. Nurses can play an important part in ensuring early diagnosis

Histopathology of lymph node tissues can demonstrate a variety of findings, from an acute abscess to chronic granulomatosis. Culture, however, is rarely useful because the intracellular pathogens grow poorly in standard culture media.

Tularemia of the head and neck: A possible sign of bioterrorism. (Original Article)

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