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cinchona

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cinchona

1. any tree or shrub of the South American rubiaceous genus Cinchona, esp C. calisaya, having medicinal bark
2. the dried bark of any of these trees, which yields quinine and other medicinal alkaloids
3. any of the drugs derived from cinchona bark
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005

cinchona

[siŋ′kō·nə]
(botany)
The dried, alkaloid-containing bark of trees of the genus Cinchona.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

cinchona

of Ecuador. [Flower Symbolism: WB, 7: 264]
Allusions—Cultural, Literary, Biblical, and Historical: A Thematic Dictionary. Copyright 2008 The Gale Group, Inc. All rights reserved.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Cinchona

 

a genus of evergreen tree of the family Rubiaceae. The trees are 10–15 m tall (some up to 25 m). The leaves are opposite, leathery, and entire. The pentamerous, tubular flowers are in cymose umbels, gathered into panicles. The corolla is pink or yellowish white and has lobes that are pubescent on the limb. The fruit is a dehiscent, bilocular, many-seeded, elongate capsule.

There are about 40 species, distributed in South America between 10° N lat. and 19° S lat. The trees grow at elevations of 1,600–2,400 m above sea level in forests on the eastern slopes of the Andes (C. officinalis is found at elevations to 3,300 m above sea level). The bark and other parts of the cinchona tree contain quinine, cinchonine, and other alkaloids that have antimalarial, tonic, and antiseptic effects. Since the 17th century, the tree has been greatly exploited for the healing properties of its bark. Despite a ban on export, Europeans sent cinchona seeds and seedlings to Java and India, where plantations were established. As a result of selection, the alkaloid content in the bark was raised from 2–2.5 percent to 16 percent. Several species, including C. ledgeriana, C. officinalis, and C. succirubra, and numerous hybrid forms are cultivated. In the USSR the cinchona tree is cultivated as an annual crop on the Black Sea coast of the Caucasus; cuttings and ovaries are preserved for the winter in hothouses. Cinchona culture is being curtailed as a result of the synthetic manufacture of its alkaloids.

REFERENCES

Atlas lekarstvennykh rastenii SSSR. Moscow, 1962.
Zhukovskii, P. M. Kul’turnye rasteniia i ikh sorodichi, 3rd ed. Leningrad, 1971.
Murav’eva, D. A., and A. F. Gammerman. Tropicheskie i subtropicheskie lekarslvennye rasteniia. Moscow, 1974.

S. S. MORSHCHIKHINA

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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References in periodicals archive
In the spring, Podbielski infused simple syrup with local cherry tree blossoms, to sweeten a tonic base of equal parts cinchona and cherry barks.
Ohashi, Transformation of Cinchona Alkaloids into 1-N-Oxide Derivatives by Endophytic Xylaria sp.
Cinchona Cruz-Gonzales, and Deputy Ombudsman Gerard Mosquera.
In 1856, William Perkins, a London chemist, was trying to synthesise quinine, a malaria treatment made from cinchona bark.
Cinchona Cruz-Gonzales (Citizen's Battle Against Corruption), private practitioner Joe-Santos Bisquera (Bisquera Balagtas Law Center).
The anti-malarial quinine comes from the bark of the Cinchona tree and salicylic acid, the basis of aspirin, is found in willow bark.
It was during the translation of a medical book that he came across the claim that a drug made from the bark of a tree called cinchona, used in the treatment of malaria, was effective due to its astringency.
From the Quechua kina, "bark," quinine is an alkaloid of cinchona that has antimalarial properties.
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