Below, the main findings of these studies are reviewed for the benefit of the new readership, to highlight the experimental work providing strong evidence in support of a putative etiopathogenic
cocarcinogenic role of SV40 in MM, despite the data from molecular and epidemiologic analyses showing moderately strong but controversial association.
Although the exact mechanisms through which alcohol exerts its
cocarcinogenic effect on the breast remain unknown, a genetic predisposition may play an important role.
Active HSV-1 immunization prevents the
cocarcinogenic activity of HSV-1 in the oral cavity of hamsters.
Hecker E (1968)
Cocarcinogenic principles from the seed oil of Croton tiglium and from other Euphorbiaceae.
Among the reasons cited for the beneficial role of fruit and vegetables in this area are that dietary fibre decreases the body's production of secondary bile acids which have been found to be
cocarcinogenic in tests conducted on rodents.
Still other components in ETS are either
cocarcinogenic tumor initiators or tumor accelerants.
Cocarcinogenic effects of alcohol in hepatocarcinogenesis.
Vitamin E and organose-lenium prevent the
cocarcinogenic activity of arsenite with solar UVR in mouse skin.
These data provide further evidence to support the ability of As to inhibit the DNA repair machinery, which is likely to enhance the genotoxicity and mutagenicity of other directly genotoxic compounds, as part of a
cocarcinogenic mechanism of action.
(1999) found no evidence for a
cocarcinogenic or tumor-promoting effect of MF exposure, but the study used different substrains of SD rats than used in the original study.