Nosocomial endocarditis caused by Corynebacterium amycolatum and other non-diphtheriae
corynebacteria. Emerg infect Dis.
Our results highlight the need to identify
corynebacteria to the species level, which is now readily performed by using MALDI-TOF mass spectrometry, and perform susceptibility testing for any isolate that is believed to be clinically meaningful.
Results: Among 493 (44.1%) cases detected positive for
corynebacteria 71.8 per cent were pharyngeal, 20.9 per cent nasopharyngeal and rest 7.3 per cent nasal diphtheria cases.
Comparison of phenotypic and genotypic methods for detection of diphtheria toxin among isolates of pathogenic
corynebacteria. J Clin Microbiol 1998;36:3173-7.
However, the extract was highly effective against selected aerobic and anaerobic bacteria such as Streptococcae,
Corynebacteria, C.
Oudin et al., "First description of NOD2 variant associated with defective neutrophil responses in a woman with granulomatous mastitis related to
corynebacteria," Journal of Clinical Microbiology, vol.
Non diphtherial
Corynebacteria also cause chronic and subclinical diseases in domestic animals and lead to significant economic losses for farmers.
A modified Elek test for detection of toxigenic
corynebacteria in the diagnostic laboratory.
Since introduction of vaccine against the diphtheria toxin in the 1940s, infections caused by toxigenic
corynebacteria have been well controlled in industrialized countries that have high coverage rates of childhood vaccination with 3 doses of diphtheria-tetanus-pertussis vaccine (1).
Clinical diphtheria is caused by toxin-producing
corynebacteria. Three species (Corynebacterium diphtheriae, C.
diphtheriae isolates sent during 1993 through 2010 to the French National Reference Centre of Toxigenic
Corynebacteria. The isolates came from metropolitan France and French overseas departments and territories.