It is an important anti-inflammatory marker of cytokine signaling gene and is encoded by the
cytokine receptor family.
We questioned whether ASC populations are heterogenic in their cytokine secretion and
cytokine receptor expression profile.
We further analyzed the largest protein category, receptor, and found four subcategories: G-protein coupled receptor,
cytokine receptor, ligand-gated ion channel, and protein kinase receptor.
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel
cytokine receptor subunit, IL-23R.
In the acute phase of mental illness, elevations have been found in both interleukin-6 (IL-6) and the
cytokine receptor soluble IL-2 (SIL-2R); for MDD and schizophrenia, cytokine levels are acutely increased, tend to decrease with treatment, and eventually rise again, he said.
However, none of our patients were treated with anticytokine therapy, such as
cytokine receptor antibodies, cytokine signaling inhibitors, TNF-[alpha] blockers, or thalidomide.
Levels of
cytokine receptor activator of nuclear factor kappa B ligand in gingival crevicular fluid in untreated chronic periodontitis patients.
Timans et al., "A receptor for the heterodimeric cytokine IL-23 is composed of IL-12R[beta]1 and a novel
cytokine receptor subunit, IL-23R," The Journal of Immunology, vol.
SOCS proteins can modulate
cytokine receptor signalling by multiple complementary mechanisms (Figure 4).
To this end we considered a group of
cytokine receptor genes which are orthologous in Mouse and Human, two species which diverged quite recently, some 65-85 MYA (million years ago) [32, 33].