The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Dehydrogenases

enzymes that catalyze the removal of hydrogen from organic compounds. The coenzymes of dehydrogenases are usually dinucleotides: nicotinamide adenine dinucleotide (NAD), nicotinamide adenine dinucleotide phosphate (NADP), or flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), which accept hydrogen from the oxidizable substance. Dehydrogenases bring about the first stage of biological oxidation and play a large part in the Krebs cycle, glycolysis, and the pentose phosphate cycle. In the organism the NADP, reduced through the action of certain dehydrogenases, is used to synthesize fatty acids. Some dehydrogenases, unconnected with coenzymes, catalyze the direct oxidation of substances by oxygen. Many dehydrogenases contain metals (zinc or manganese) that are part of their active centers.

G. Z. SOLOV’EVA

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References in periodicals archive

Accordingly, certain cancers are associated with genetic aberrations in TCA cycle enzymes, such as isocitrate dehydrogenase 1 (IDH1), isocitrate dehydrogenase 2 (IDH2), succinate dehydrogenase (SDH), fumarate hydratase (FH), and L-2-hydroxyglutarate dehydrogenase.

Oncometabolites: A New Paradigm for Oncology, Metabolism, and the Clinical Laboratory

The analyzed proteins include the complex I or NADH dehydrogenase subunits, the A and B subunits of complex II or succinate dehydrogenase, and various subunits of complex III or cytochrome bcl.

CRUSTACEAN BIOENERGETICS: MITOCHONDRIAL ADAPTIVE MOLECULAR RESPONSES TO FACE ENVIRONMENTAL CHALLENGES

Lactate dehydrogenases and malate dehydrogenases in sperm: studied by polyacrylamide gel electrophoresis.

Expression of Ldh-c (Sperm-Specific Lactate Dehydrogenase Gene) in Skeletal Muscle of Plateau Pika, Ochotona curzoniae, and its Effect on Anaerobic Glycolysis

Cook, "Racemase activity effected by two dehydrogenases in sulfolactate degradation by Chromohalobacter salexigens: purification of (S)-sulfolactate dehydrogenase," Microbiology, vol.

Expression, Purification, and Characterization of (R)-Sulfolactate Dehydrogenase (ComC) from the Rumen Methanogen Methanobrevibacter millerae SM9

Aldehyde dehydrogenase 2 (ALDH2) is a homotetramer enzyme located in the mitochondrial matrix.

Association between Carotid Intima-media Thickness and Aldehyde Dehydrogenase 2 Glu504Lys Polymorphism in Chinese Han with Essential Hypertension

Of these patients 59% were diagnosed as IDA.3 Glucose-6phosphate dehydrogenase (G6PD) catalyzes the rate-determining step in the pentose phosphate pathway and produces NADPH to fuel glutathione recycling.

The investigation of plasma glucose-6-phosphate dehydrogenase 6-phoshogluconate dehydrogenase glutathione reductase in premenauposal patients with iron deficiency anemia

The objectives of this study were (1) to quantify the activities of five soil enzymes (invertase, urease, phosphatase, catalase, and dehydrogenase) and selected soil physicochemical properties across an entire county (Changwu) on the Loess Plateau; (2) to investigate the spatial variability of soil enzyme activities in a representative area in the Hilly-Gully Region of Loess Plateau; and (3) to explore the relationships between soil enzyme activities and physicochemical properties using an integrated soil enzyme activity index (TEI) and to compare it with the geometric mean of enzyme activities (GME).

County-scale spatial distribution of soil enzyme activities and enzyme activity indices in agricultural land: implications for soil quality assessment

In the bacterium Clostridium kluyveri an NAD(P)H-dependent flavoenzyme dihydrolipoyl dehydrogenase (synonymously called dihydrolipoamide dehydrogenase) reduces Fe(III) complexes of citrate, ATP, and ADP [2].

Identification of multiple soluble Fe(III) reductases in gram-positive thermophilic bacterium Thermoanaerobacter indiensis BSB-33

Glucose-6-phosphate dehydrogenase (G6PD, EC 1.1.1.49, [beta]-D-glucose-6-phosphate; NADP oxidoreductase) is the initial and the key regulatory enzyme in the pentose phosphate pathway [1-4].

Purification and characterization of glucose-6-phosphate dehydrogenase from camel liver

(iii) related enzymes may exhibit SI in some conditions, as is the case glutamate dehydrogenase [4].

What happens when the wrong equation is fitted to data?