This process operates continuously and independently of
exocytotic catecholamine release, providing an advantage for measurements of metanephrines during diagnosis of tumors that release catecholamines episodically or in low amounts (Fig.
The aim of this study was to evaluate the effects of the anti-cholinesterase pesticides methyl-parathion and carbaryl on the changes in the expression of the
exocytotic membrane proteins Syntaxin-1, Syntaxin-4 and SNAP-23 in the rotifer B.
They are believed to be the integral part of
exocytotic pathways due to their spatio-temporal patterns in cytosol generated by the subtle interplay between intracellular calcium source and its removal.
The novel insulinotropic mechanism of pimobendan: direct enhancement of the
exocytotic process of insulin secretory granules by increased [Ca2.sup.+] sensitivity in beta-cells.
Midrier, "Time-resolved dynamics of the vesicle membrane during individual
exocytotic secretion events, as extracted from amperometric monitoring of adrenaline exocytosis from chromaffin cells," Chemistry--A European Journal, vol.
The increased levels of ATP result in the closure of ATP-sensitive potassium channels, which leads to a depolarization of the membrane and subsequent opening of voltage-dependent calcium channels and the influx of calcium resulting in the rise of cytoplasmic-free calcium concentration and activation of the
exocytotic machinery [9].
There are two levels in the control of GH secretion: the
exocytotic pathway responsible for release of prestored hormone (short term) and de novo synthesis (long term).
Two prior studies have reported higher sensitivity to BoNT-A at 33 fM [49] and 400fM [15], although the physiological significance of low levels of protein cleavage to the
exocytotic process is unclear.
Lansman, "Neurotensin stimulates
exocytotic histamine secretion from rat mast cells and elevates plasma histamine levels," Journal of Physiology, vol.
The MHC Ipeptide complexes are transported to the cell membrane in
exocytotic vesicles via the Golgi apparatus.