Teniendo en cuenta lo anterior, un estudio realizado por Cordeiro y colaboradores (32) evaluo los efectos del
farnesol en la susceptibilidad antifungica de especimenes de Candida con resistencia in vitro a anfotericina B, azoles y caspofungina.
Identification of a nuclear receptor that is activated by
farnesol metabolites.
Table 2: GCMS of plant extracts and fractions Lactuca serriola Farsetia aegyptia Santolina chamaecyparissus Lupan-3-ol-acetate Coumaran Vanillin Urs-12-ene Vanillin
Farnesol Sclareol - Humuladienone d-Orandrostane Quinic acid Lanosterin 4,4-Dimethylandrost- 2-Pyrrolidinone Gamm-sitosterol 1-en-3-one 1,2-Epoxycholestan- piperidin-2-imine Cyclolaudenol 3-one - Pyrrolidinone, Urs-12-en 1,2-hydroxyethyl Chrysene Chrysene, 1,2,3,4, 3-O-Acetyl-delta-24- 4a,4b,5,6,10,10a, cycloartenol 10b,11-dodecahydro - 3-O-Acetyl-6-methoxy- 9,19-Cyclolanost-24- cycloartenol en-3-oil, acetate, (3beta) 9,19-Cyclolanost-23- - 9,19-Cyclolanost-23- ene-3,25-diol, ene-3,25-diol, 3-acetate, 3-acetate, (3beta,23E) (3.beta,23E)
The fruit contain higher bitter principle, tannins and essential oil (9-10%), consisting of anethole (85-90%), a-pinene, limone, b-phellandrene, a-terpineol,
farnesol and safrol.
Burke, Y.D., Stark, M.J., Roach, S.L., Sen, S.E., Crowell, P.L., 1997, Inhibition of pancreatic cancer growth by the dietary isoprenoids
farnesol and geraniol.
The later step in MF biosynthesis is unique to arthropods and consists of a series of enzymatic reactions beginning with conversion of FPP to
farnesol, then to farnesoic acid (FA), and finally to MF (Borst et al., 2001).
The cells were then treated with irrigants for 5 minutes at 37[degrees]C including the most commonly used ones: 3% and 6% NaOCl and chlorohexidine, and natural substances including 0.2%
farnesol, 5% or 20% xylitol, 20mM salicylic acid, mixtures of the natural substances, and saline (control).
The special type of pheromones which secreted by the male from the cephalic labial gland has been identified as
farnesol. The young unmated queens also secrete sex pheromones from their mandibular glands to attract the males (van Honk et al.
gordonii are capable of promoting or attenuating the hyphal growth either by physical interactions or chemical signaling via production of quorum sensing molecules like
farnesol and tyresol which are negative and positive regulators of morphogenesis respectively.