Among their cases are a comparison two cases of 19th-century
general paresis in Guy de Maupassant and Friedrich Nietzsche, substance abuse versus epilepsy in Edgar Allan Poe, Immanuel Kant's evolution from a personality disorder to a dementia, bipolar disorder as an explanation of Van Gogh's night, the terminal illness and last compositions of Maurice Ravel, Georg Friedrich Handel's strokes, and music and brain in Gershwin and Shebalin.