The
Germfree platform promotes scalability essential in the early stages of drug development.
coli, or Clostridium species into
germfree mice resulted in a remarkable increase in the levels of biologically active dopamine and norepinephrine.
Another study with mice genetically predisposed to develop EAE showed that when they were housed in
germfree or pathogen-free conditions, they were protected from developing EAE.
Originally formed in London in 1976, the original line-up only managed one album,
Germfree Adolescents, before splitting in 1979.
The sterilizing, cooking and sealing process are managed by NASA Class 100 standard in order to produce complete
germfree packed rice, without adding any chemicals or food addictives.
Mice fed the same diet and colonized with bifidobacteria, meanwhile, remained lean, as did
germfree mice.
Use of the
germfree animal technic in the study of experimental dental caries.
One loop full of overnight grown Bt culture from LB agar plate was taken and suspended in 1500ul of
germfree distilled water, centrifuged at 9,000 x g for 2 minutes at 4degC.
Female rats weighing 125-175 g (CD, Charles River Breeding Farms, Wilmington, MA, USA) or
germfree female rats of similar weight (Taconic Farms, NY, USA) were used throughout these studies and maintained in accordance with the guidelines of the Committee on Animals of the Harvard Medical School and those prepared by the Committee on Care and Use of Laboratory Animals, the Institute of Laboratory Animal Resources, National Research Council (DHEW, Publication No.
Lambre et al., "Development of a heterologous model in
germfree suckling rats for studies of rotavirus diarrhea," Journal of Virology, vol.
Imbalance of the normal microbial flora: The
germfree alimentary tract.