Atkinson, "Complement regulatory genes and
hemolytic uremic syndromes," Annual Review of Medicine, vol.
Ocular involvement in
hemolytic uremic syndrome due to factor H deficiency are there therapeutic consequences.
Prophylactic eculizumab prior to kidney transplantation for atypical
hemolytic uremic syndrome. Pediatr Nephrol 2011;26:1325-9.
* The report provides a snapshot of the global therapeutic landscape of Atypical
Hemolytic Uremic Syndrome (Nondiarrhea- Associated
Hemolytic Uremic Syndrome)
Hemolytic uremic syndrome has different etiological classifications in the literature (2, 5-7).
"Update on
hemolytic uremic syndrome: diagnostic and therapeutic recommendations." World journal of nephrology 2.3 (2013): 56.
Abbreviations: ADAHTS13, a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13; aHUS, atypical
hemolytic uremic syndrome; A-TTP, acquired thrombotic thrombocytopenic purpura; CTTP, congenital thrombotic thrombocytopenic purpura; HUS,
hemolytic uremic syndrome; SPHUS, Streptococcus pneumoniae-associated
hemolytic uremic syndrome; STEC-HUS, Shiga toxin-producing, Escherichia coli-associated
hemolytic uremic syndrome; TPE, therapeutic plasma exchange.
Functional characterization of two novel non synonymous alterations in CD46 and a Q950H change in factor H found in atypical
hemolytic uremic syndrome patients.
Efficacy of eculizumab in a patient with factor-H-associated atypical
hemolytic uremic syndrome. Pediatric Nephrology, 26(4), 621-624.
Hemolytic uremic syndrome; pathogenesis, treatment, and outcome.
We also reviewed case records in the literature via search of PubMed using the terms of atypical
hemolytic uremic syndrome and eculizumab and included cases with platelet counts within the first 7 days for assessment.