Different molecular forces of protein-protein interactions during heating process contributed to form and maintain the gelation structures, which included ionic bonds, hydrogen bonds and
hydrophobic interactions [14].
The adsorption of alkyl sulfate surfactants onto [gamma]-[Al.sub.2][O.sub.3] was induced by electrostatic and
hydrophobic interactions. However, the
hydrophobic interaction is much stronger for STS adsorption than for SDS adsorption.
The hydrophobic tail moiety of Rosiglitazone may also interact with helix 3, 5, 6, 7, and the [beta] strand, occupying arm II and arm III of the LBD, through van der Waals and
hydrophobic interactions which accounts for the efficiency of binding and potency of the molecule.
Also, their conformations have to be stable (e.g., stabilized by
hydrophobic interaction around aromatic residue).
Hydrophobic interaction in tannin-protein complexes.
Purification of monoclonal antibodies by
hydrophobic interaction chromatography under no-salt conditions.
(6) An example of entropic repulsion is when a nonionic surfactant anchors onto the latex particle via a
hydrophobic interaction, and the hydrophilic portion extends into the water phase and attains a high degree of conformational freedom.
Tannin structure variation has been shown to influence the extent of
hydrophobic interaction and it can be quantitatively measured.
The originator molecule was characterized using, among other analyses, oligosaccharide mapping, peptide mapping (by MS), size exclusion FTPLC, ion exchange HPLC,
hydrophobic interaction HPLC, SDS and IEF capillary electrophoresis, cellbased bioassay (ligand inhibition assay) and OCTET analyses of the binding kinetics of both the Fc and CDR portions of the mAb to their appropriate targets.