These data corroborate the findings of a smaller study evaluating
hydroxychloroquine for oral lichen planus, published in 1993, according to Dr.
Treatment of scleromyxoedema with
hydroxychloroquine. J Dtsch Dermatol Ges 2003; 1:30-35.
The incidence of irreversible retinal toxicity in patients treated with
hydroxychloroquine: a reappraisal.
The total number of patients on ramipril in both the groups were 16/31 in the
Hydroxychloroquine group and 22/36 in the non-Hydroxychloroquine group, respectively based on whether their eGFR permitted use of ramipril or not.
Consequently, we proposed treatment with
hydroxychloroquine given its anti-inflammatory and antiproliferative actions.
Extensive discoid lupus erythematosus in a HIV patient responding to
hydroxychloroquine monotherapy.
They performed a randomized, double-blind clinical trial, the Persistent Lyme Empiric Antibiotic Study Europe (PLEASE), in which 280 adults (mean age, 49 years) received daily 2,000-mg open-label IV ceftriaxone for 14 days and then were assigned to receive 100 mg oral doxycycline twice daily plus placebo (86 patients), combined 500 mg clarithromycin twice daily plus 200 mg
hydroxychloroquine twice daily (96 patients), or two placebo capsules twice daily (98 patients) for 12 weeks.
All patients also began a regimen of DMARDs (methotrexate, sulfasalazine, and
hydroxychloroquine).
A drug called
hydroxychloroquine being the last drug was approved by FDA in 1955 for SLE treatment.