Due to the persistence of severe hyponatremia (123.8 mmol/L) and symptoms such as asthenia and nausea 19 days later,
hypoadrenalism was suspected.
Thus, there is the potential that these patients would manifest
hypoadrenalism if tapered from their postoperative steroids too quickly, resulting in
hypoadrenalism symptoms such as nausea, vomiting, headache, and possible circulatory collapse.
IT'S a rare disorder of the adrenal glands (found on top of kidneys) often known as
hypoadrenalism. It affects around 1 in 10,000 people - commoly between ages of 30-50.
potential
hypoadrenalism. Therefore, her severe life-threatening autoimmune condition might benefit from glucocorticoids, e.g.
The tumour appears to have eroded the sellar floor, extending into and displacing the pituitary gland, causing secondary
hypoadrenalism.
Other notable endocrine conditions recorded as a primary or secondary contributory causes of death were 'Addison's Disease' or 'Adrenocortical Insufficiency'/'
Hypoadrenalism' (2 entries) and 'Hypothyroidism' (1 entry).
However, most patients with a sizable pituitary lesion are at risk for
hypoadrenalism (Ben-Shalomo & Melmed, 2011); therefore, a prophylactic stress dose of glucocorticoid, hydrocortisone (100 mg), is usually given intravenously during the immediate perioperative period of TS surgery except for patients with Cushing disease (Barkan et al., 2008).
When the hypothalamus and hypophysis are affected, polydipsia, diabetes insipidus, hypogonadism,
hypoadrenalism, hypothyroidism and, less frequently, hyperprolactinemia might be seen.
This case describes a patient with a non-functioning pituitary macroadenoma, who had secondary hypogonadism and
hypoadrenalism. Locally advanced prostate cancer was detected 18 to 24 months after the start of testosterone supplementation.
Adrenal insufficiency ranges from subclinical
hypoadrenalism to overt primary adrenal insufficiency.