Encyclopedia

isoflurophate

isoflurophate

[‚ī·sə′flu̇r·ə‚fāt]
(pharmacology)
[(CH3)2CHO]2P(O)F A liquid that forms hydrofluoric acid in the presence of moisture: used as a cholinergic drug in eye diseases in humans and as a miotic drug in animals.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
Compound Docking scores (kcal x [mol.sup.-1]) Trichlorfon -5.7 Echothiophate -5.9 Isoflurophate -5.9 Pyridostigmine -6.3 Neostigmine -7.5 Parathion -7.6 Rivastigmine -7.9 Tacrine -8.8 Ladostigil -9.1 Physostigmine -9.1 Huperzine A -9.7 Ungeremine -10 Galantamine -10.2 Donepezil -12.1 2 -9.1 3 -9.4 6 -7.8 7 -5.7 8 -7.6 9 -7.9 14 -10
Topical application of 0.03% echothiophate iodide or 0.025% Isoflurophate (both organophosphates) has been successful for T.
Examples of organophosphates include insecticides (Malathion, parathion, diazinon, fenthion, dichlorvos, chlorpyrifos, ethion), nerve gases (Soman, sarin, tabun, VX), ophthalmic agents (Echothiophate, isoflurophate), and anthelmintics (Trichlorfon).
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