ketosis

[kē′tō·səs]

(medicine)

Excess amounts of ketones in the body, especially associated with diabetes mellitus. Also known as ketoacidosis.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Ketosis

acetonemia, a disease of cows and sheep characterized by metabolic disturbance (carbohydrate-fat and protein). Affected are highly productive cows in the second to sixth week of lactation and multiparous sheep one to two weeks before lambing. The principal cause of ketosis is a carbohydrate deficiency connected with a dietary imbalance with respect to carbohydrate and protein. High milk yield, multiparity, and lack of exercise predispose to ketosis.

In sheep, ketosis develops predominantly when feeding is inadequate and the body is forced to meet its demand for nutritive substances at the expense of deposited fat.

The affected animals suffer digestive disturbances (decrease or perversion of appetite and weakening of the peristaltic and secretory activities of the digestive glands) and show an increase in the number of ketone bodies in the blood, urine, and milk. There is a decrease in milk productivity and a loss of weight. Nervous disturbances (agitation, depression) and a disruption of liver function are also observed. If untreated, the disease usually ends in the death of the animal. Treatment involves proper diet, intravenous injection of glucose, and the use of hormonal preparations. Ketosis can be prevented by properly feeding and keeping the animals.

A. M. KOLESOV

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References in periodicals archive

Comparison of Parameters in Ketotic Group and Non-Ketotic Group Parameters Group Total Mean Std.

CLINICO-LABORATORY CHARACTERISTICS AND IMMEDIATE OUTCOME IN CHILDREN WITH DIABETES MELLITUS

(2017) Number of patients 1 6 Skeletal malformations Short stature + - (0/6) Fractures - + (4/6) Anteverted nares + Small upturned nose + Hypertelorism + Frontal bossing + Short proximal bones + Hypermobile joints + Dislocating joints - + (3/6) Joint laxity - Diffuse demineralisation - Downslanting palpebral fissures + Congenital heart defects + (3/7) Ventricular septal defect + Pulmonary stenosis + Bicuspid aortic valve - Aortic root dilation - Mitral valve prolapse - Neurological Small anterior pituitary + Partially empty sella Other features TSH abnormality - Cognitive delay - Stillborn sibling + GH deficiency + Congenital sensorineural deafness + Ketotic hypoglycaemia + Phenotype Baasanjav et al.

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