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khellin

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khellin

[′kel·ən]
(pharmacology)
C14H12O5 A synthetic compound that crystallizes from methanol solution, has a bitter taste, melts at 154-155°C, and is more soluble in water than in organic solvents; used in medicine as an antispasmodic, a coronary vasodilator, and a bronchodilator. Also spelled chellin; khelin. Also known as visammin.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
Khellin is an extract from the Mediterranean khella plant that is thought to stimulate melanocyte proliferation and melanogenesis.
[7] Novel systemic therapies like L-phenylalanine, Polypodium leucotomos, Khellin, Ginkgo biloba, vitamins B12, C, E, folic acid and zinc have also been found to be effective.
It has been documented that 38 medicinal plants including Ammi visnaga have natural calcium channel blocker.2 Khellin and visnagin were identified from Ammi visnaga fruit and were proved that all of them have calcium channel blocking mode of action.3
Therapy of heart disease with khellin, with special reference to the khellinstrophanthin.
It was the aim of our study to evaluate the effect of a Khella extract (KE) as well as the two major constituents khellin and visnagin on renal epithelial injury using LLC-PK1 and Madin-Darby-canine kidney (MDCK) cells.
Conventional antiasthmatic compounds, such as sodium cromolyn and sodium cromoglycate, were developed from analogs of the naturally occurring furanochromone khellin (visammin), found in the Asian plant Ammi visnaga.
Bashar Mohammad Harb Hamad In recognition of a programme of work entitled, "Synthesis and Pharmacological Evaluation of Novel Khellin Analogues as Potential Cardioprotective Agents", carried out at Coventry University, under the direction and supervision of Dr T Javed, Senior Lecturer, School of Science and the Environment, Coventry University and Dr S O Fagbemi, Senior Lecturer, Department of Forensic and Biomedical Sciences, Faculty of Health Life and Social Sciences, University of Lincoln.
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