Spontaneous Tumor Lysis Syndrome in Childhood T cell Acute
Lymphoblastic Leukemia. Oman Med J.
Hyperdiploid acute
lymphoblastic leukemia with 51 to 65 chromosomes: a distinct biological entity with a marked propensity to undergo apoptosis.
T-acute
lymphoblastic leukemia with cytoplasmic granules.
At that time, Sprycel also received FDA approval for adults with Ph+ acute
lymphoblastic leukemia who are resistant or intolerant to prior therapy.
Acute
Lymphoblastic Leukemia (ALL) is a rare blood cancer affecting the maturation of B-cell and T-cell lymphoblasts from progenitor cells.
Advances in acute
lymphoblastic leukemia in adults.
"Glial injury may be present at diagnosis of acute
lymphoblastic leukemia. Neuronal injury was associated with intrathecal chemotherapy," the authors write.
The correct and rapid determination of the subtypes of acute
lymphoblastic leukemia plays a crucial role in assessing the best risk oriented treatment for the patient to improve treatment outcomes.
Out of these, 23 cases (58.97%) were of acute leukemia including both acute myeloid and acute lymphocytic leukemia; nine cases (23.07%) were of acute leukemia while eight cases (20.15%) of acute myeloid and 06 cases (15.38%) of acute
lymphoblastic leukemia. Five cases (12.83%) of multiple myeloma were reported and 4 cases of chronic myeloid leukemia (10.25%).5
Conclusion: Acute
Lymphoblastic Leukemia and Wilm's tumor is the most prevalent cancer in all age groups, being greatest among early childhood years (1-5) affecting more males than females.
Clinically defining and managing high-risk pediatric patients with acute
lymphoblastic leukemia. American Society of Hematology Education Program, 2014(1):181-189.