The investment forms part of Recipharm's strategy to become a leading
lyophilisation provider, and is in addition to the ongoing investment at Recipharm in Wasserburg, Germany, where a further 32 million is currently being spent to increase capacity.
Porous chitosan structures are formed by freezing and
lyophilisation. During the freezing process, ice crystals are formed.
Following heat-killing and subsequent
lyophilisation, LPS was recovered using a previously described hot-phenol extraction method [15, 26].
Subfraction
Lyophilisation of Hydroethanol Extract.
Batch
lyophilisation is crucial in reducing overall extraction time.
A correction for gravimetric water content (Eqn 2) was not applied to the measured OC values obtained for the coarse or fine fractions since they were dried completely by
lyophilisation before analysis.
Other methods of improving the yield of cells include
lyophilisation of cells [27] and novel storage methods.
The
lyophilisation process was more efficient for removing water from the material and resulted in a product with higher content of lipids.
Freeze-drying (also known as
lyophilisation or cryodesiccation) is a dehydration process typically used to preserve perishable materials or make materials lighter or more convenient for transport.
The cells were then dried by
lyophilisation in the freeze dryer (FTS System, U) (Adwitiya et al., 2009).