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megaloblast

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megaloblast

[′meg·ə·lō‚blast]
(pathology)
A large nucleated erythroblast appearing in bone marrow in vitamin B12 or folic acid deficiency.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
Diagnosis requires blood tests to look for megaloblasts and measure levels of B12 and folic acid.
MEGALOBLASTIC C ANAEMIA
The earliest sign of folic acid or vitamin [B.sub.12] deficiency is a megaloblastic anemia - so-called because of the abnormal production of megaloblasts, the precursors of mature red cells.
Folate - the "wonder vitamin." (part 1)
Megaloblastic Anaemia- Megaloblasts, Giant Stab and Metamyelocyte in BM Aspirate (100x)
PANCYTOPENIA- A CLINICO-HAEMATOLOGICAL STUDY
The bone marrow aspiration of megaloblastic anaemia showed numerous megaloblasts with large cells with an increased nuclear/cytoplasmic ratio, sieve-like chromatin and giant metamyelocytes (Figure B).
A two years study of showcasing the role of bone marrow aspiration in diagnosing the spectrum of haematological disorders in a tertiary care hospital
MA had typical megaloblasts with sieved chromatin and asynchronic nuclear-cytoplasmic maturation (Figure 1).
Bone marrow examination in pancytopenia: a study of six years
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