The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Melanosis

the intensified formation and deposit in organs and tissues of a dark brown or black pigment of the melanin group (normally present in the skin, retina, and meninges).

A distinction is made between congenital melanosis and acquired melanosis. The former includes congenital melanosis of the skin (melanoderma), manifested by freckles or pigmented birthmarks. Acquired melanosis frequently develops as a result of a change in endocrine function (adrenal, pituitary, or gonadal). The pigmentation may be diffuse (for example, in Addison’s disease) or circumscribed (for example, during pregnancy, on the face and around the nipples). The condition may also be caused by systemic poisoning by hydrocarbons (toxic melanoderma) or by physical, mechanical, or chemical irritation (light, heat, the distillate products of coal).

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References in periodicals archive

Muller, "Melanotic neuroectodermal tumour of infancy: report of two cases and review of the literature," Journal of Cranio-Maxillo-Facial Surgery, vol.

Postauricular Melanocytic Neuroectodermal Tumor of Infancy: A Rare Site of a Rare Tumor--MNTI as a Postauricular Mass with Literature Review

Melanotic lesions of prostate: Blue nevus and prostatic epithelial melanosis," Urology, vol.

A Rare Case of Multifocal Prostatic Blue Nevus

Our patient's persistent melanotic stools draw attention to the ongoing risk of rebleeding in patients after pancreatic pseudoaneurysm embolization.

Hemosuccus Pancreaticus: A Rare Bleeding Pseudoaneurysm of the Inferior Pancreaticoduodenal Artery Treated with Embolization

Melanotic visceral fibrosis associated with larval infections of Posthodiplostomum minimum and Proteocephalus sp.

TEMPORAL OCCURRENCE OF THE METACERCARIA OF POSTHODIPLOSTOMUM MINIMUM (TREMATODA : STRIGEIDAE) AND OTHER PARASITIC HELMINTHS OF BLUEGILL (CENTRARCHIDAE: LEPOMIS MACROCHIRUS) IN A EUTROPHIC MEANDER SCAR LAKE IN SOUTHEAST TEXAS

Solitary gastric melanotic schwannoma: sonographic findings.

GASTRIC SCHWANNOMA - A CASE REPORT

Oral mucosal melanoma usually develops de novo in clinically normal-looking mucosa, but it has been reported that in up to one-third of cases it arises from within areas of benign oral melanotic hyperpigmentation of the oral mucosa [6].

A Review of the Aetiopathogenesis and Clinical and Histopathological Features of Oral Mucosal Melanoma

The necrotic and degenerated tissues are removed by phagocytes and replaced by neuroglial cells, leading to the formation of cystic, melanotic and colloidal lesions at the injured site within 6 weeks after the injury.

Therapeutic Potential of Olfactory Ensheathing Cells and Mesenchymal Stem Cells in Spinal Cord Injuries

Soon, "Solitary gastric melanotic schwannoma: sonographic findings," Journal of Clinical Ultrasound, vol.

Gastric Schwannoma: A Tumor Must Be Included in Differential Diagnoses of Gastric Submucosal Tumors

Caption: Figure 1: Presence of several medium size melanotic lesions in the fundus and the body of the stomach.

Gastric and Rectal Metastases from Malignant Melanoma Presenting with Hypochromic Anemia and Treated with Immunotherapy

Although Antoni A and Antoni B areas are seen in various ratios in classic schwannoma, varying morphologies have been described, including ancient, cellular, melanotic, plexiform, glandular, and epithelioid subtypes [5].

Schwannoma Localized Retroperitoneally in a 14-Year-Old Boy

Pathological types of tumors included schwannoma (31 cases) [Figure 5], epidermoid cyst (12 cases), neurofibroma (5 cases), hemangioma (2 cases), and melanotic schwannoma (1 case).

Three-dimensional Fluoroscopy-based Navigation for the Pedicle Screw Placement in Patients with Primary Invasive Spinal Tumors