Although uncommon in children, a more generalized type of follicular
mucinosis can present very similar to lichen spinulosus.
Lymphocytic infiltration of the skin (Jessner-Kanof) but not reticular erythematous
mucinosis occasionally represents clinical manifestations of Borrelia-associated pseudolymphoma.
Cutaneous
mucinosis encompasses a heterogeneous group of skin diseases characterized by the deposition of mucin in the interval of the dermis (2).
No mucin deposition within the follicles (follicular
mucinosis) was seen (figure 3c).
Other differential diagnoses include self-healing juvenile cutaneous
mucinosis and acral persistent papular
mucinosis.
SPAID, a spontaneously occurring auto-inflammatory disease, causes fever, swollen joints, cutaneous
mucinosis (a skin disorder), ear problems, and kidney failure.
Other drugs that have been associated with PCA are hepatitis B vaccines causing Graham-Little-Piccardi-Lasseur syndrome [33], anticonvulsants and cyclosporine causing acne keloidalis nuchae (AKN) [34-36], and imatinib causing follicular
mucinosis [37].
(3) Histopathologically, in addition to folliculotropism, features such as epidermotropism, syringotropism, follicular
mucinosis, and granulomatous inflammation can be seen as per the spectrum of atypical cutaneous lesions.
For example, if there is no lichenoid inflammation present histologically, the diagnosis is not lichen planus; absence of granulomata excludes sarcoidosis; lack of dermal mucin rules out a
mucinosis. When certain inflammatory cells are absent, this should also be mentioned when relevant.
The painless, 3.0-cm tumor was initially mistaken for reticular erythematous
mucinosis, a benign skin condition that occurs when fibroblasts produce abnormally large amounts of mucopolysaccharides.
Follicular
mucinosis: Skin coloured or erythematous plaques favouring scalp, face, neck and shoulders.