Myeloproliferative Disorders. Hematol Oncol Clin North Am 2017; 31(6):1029-1044.
Sustained expression of microRNA-155 in hematopoietic stem cells causes a
myeloproliferative disorder. J Exp Med 2008;205:585-94.
We report a severe NS phenotype with a horseshoe kidney, thrombocytopenia,
myeloproliferative disorder (MPD), feeding difficulty secondary to pylorospasm, and respiratory failure with pulmonary capillaritis and vasculitis.
Protein C and S deficiency, antiphospolipid syndrome,
myeloproliferative disorders, idiopathic hypereosinophilic syndrome, pheochromocytoma, and Takatsubo cardiomyopathy were reported to be related with thrombus formation in patients with a normal LV ejection fraction (8-10).
Acquired mutation of the tyrosine kinase JAK2 in human
myeloproliferative disorders. Lancet.
A prospective evaluation of primary
myeloproliferative disorders," Gastroenterology, vol.
It is associated with a multitude of conditions, including lymphoproliferative disorders (most common: 48%),
myeloproliferative disorders (chronic granulocytic leukemia, essential thrombocythemia, and polycythemia vera), neoplasms (Wilms tumor), immunological disorders, cardiovascular diseases, hypothyroidism, hemoglobinopathies, drugs (valproate, ciprofloxacin, and hydroxyethyl starch), and infections [1, 2, 4-7].
(4,5) They are rare tumors, with an incidence of 3 to 4.7% among
myeloproliferative disorders, predominantly in AML.
Patients with other causes of thrombocytopenia (inherited thrombocytopenias), bone marrow failure syndromes, lymphoproliferative disorders,
myeloproliferative disorders, thrombotic microangiopathies, megaloblastic anaemia and pseudothrombocytopenia were carefully excluded according to the findings in history, physical examination and investigations.